CL2E-SN38

Names

[ Name ]:
CL2E-SN38

Biological Activity

[Description]:

CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Lianqi Liu, et al. Synthesis and evaluation of highly releasable and structurally stable antibody-SN-38-conjugates. Drug Deliv. 2021 Dec;28(1):2603-2617.

Chemical & Physical Properties

[ Molecular Formula ]:
C₈₆H₁₁₈N₁₄O₂₄

[ Molecular Weight ]:
1731.94

Related Compounds

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