PKUMDL-LC-101-D04

Modify Date: 2024-01-11 10:35:14

PKUMDL-LC-101-D04 Structure
PKUMDL-LC-101-D04 structure
Common Name PKUMDL-LC-101-D04
CAS Number 2143896-83-5 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PKUMDL-LC-101-D04


PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts[1].

 Names

Name PKUMDL-LC-101-D04

 PKUMDL-LC-101-D04 Biological Activity

Description PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts[1].
Related Catalog
References

[1]. Li C, et al. Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4. J Med Chem. 2019;62(1):266-275.

 Chemical & Physical Properties

No Any Chemical & Physical Properties