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2143896-83-5

2143896-83-5 structure
2143896-83-5 structure
  • Name: PKUMDL-LC-101-D04
  • Chemical Name: PKUMDL-LC-101-D04
  • CAS Number: 2143896-83-5
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2021-07-28 17:35:37
  • Modify Date: 2024-01-11 10:35:14
  • PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts[1].

Name PKUMDL-LC-101-D04
Description PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts[1].
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References

[1]. Li C, et al. Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4. J Med Chem. 2019;62(1):266-275.

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