![]() HSP27 inhibitor J2 structure
|
Common Name | HSP27 inhibitor J2 | ||
---|---|---|---|---|
CAS Number | 2133499-85-9 | Molecular Weight | 264.30 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C13H12O4S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of HSP27 inhibitor J2HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition[1][2]. |
Name | HSP27 inhibitor J2 |
---|
Description | HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition[1][2]. |
---|---|
Related Catalog | |
Target |
HSP27[2] |
References |
[2]. Younghwa Na, et al. Methods for treating pulmonary fibrosis using chromenone derivatives. |
Molecular Formula | C13H12O4S |
---|---|
Molecular Weight | 264.30 |
Storage condition | -20°C |