Tyk2-IN-9
Modify Date: 2025-08-25 12:06:26
Tyk2-IN-9 structure
|
Common Name | Tyk2-IN-9 | ||
|---|---|---|---|---|
| CAS Number | 2127109-85-5 | Molecular Weight | 383.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H17N9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tyk2-IN-9Tyk2-IN-9 is a potent,selective and specific inhibitor of JAK kinases, inhibits Tyk2, JAK1 and JAK2 with IC50 values of 6 nM, 21nM and 6nM, respectively. Tyk2-IN-9, example 19, is extracted from patent US2017240552A1[1]. |
| Name | Tyk2-IN-9 |
|---|
| Description | Tyk2-IN-9 is a potent,selective and specific inhibitor of JAK kinases, inhibits Tyk2, JAK1 and JAK2 with IC50 values of 6 nM, 21nM and 6nM, respectively. Tyk2-IN-9, example 19, is extracted from patent US2017240552A1[1]. |
|---|---|
| Related Catalog | |
| Target |
Tyk2:6 nM (IC50) JAK1:21 nM (IC50) JAK2:8 nM (IC50) |
| In Vitro | Tyk2-IN-9 has the ability to inhibit IL-12 signaling in a human whole blood with an IC50 value of 28 nM in a flow cytometry assay[1]. |
| References |
[1]. Matthew Frank Brown, et al. Pyrazolo[1,5-a]pyrazin-4-yl derivatives. Patent US20170240552A1 |
| Molecular Formula | C20H17N9 |
|---|---|
| Molecular Weight | 383.41 |