PARP-2-IN-1

Modify Date: 2024-01-09 10:15:39

Use of PARP-2-IN-1

PARP-2-IN-1 is a potent and selective PARP-2 inhibitor with an IC50 of 11.5 nM.

Name	PARP-2-IN-1

Description	PARP-2-IN-1 is a potent and selective PARP-2 inhibitor with an IC50 of 11.5 nM.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	PARP-2:11.5 nM (IC50)
References	[1]. Zhao H, et al. Discovery of novel quinazoline-2,4(1H,3H)-dione derivatives as potent PARP-2 selective inhibitors. Bioorg Med Chem. 2017 Aug 1;25(15):4045-4054.

Molecular Formula	C₂₁H₁₉F₄N₅O₃
Molecular Weight	465.40