1005784-23-5

1005784-23-5 structure

1005784-23-5 structure

Name: CLK1/2-IN-1
Chemical Name: CLK1/2-IN-1
CAS Number: 1005784-23-5
Molecular Formula: C₂₁H₂₀F₃N₇O
Molecular Weight: 443.43
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2022-08-20 18:05:12
Modify Date: 2024-01-11 00:23:11
CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC50 values of 16 nM and 45 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities[1].

Name	CLK1/2-IN-1

Description	CLK1/2-IN-2 is CLK1 and CLK2 inhibitor with IC50 values of 16 nM and 45 nM, respectively. CLK1/2-IN-2 exhibits potent anti-cancer activities[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CLK1:16 nM (IC50) CLK2:45 nM (IC50)
References	[1]. Shinsuke Araki, et al. Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing. PLoS One

Molecular Formula	C₂₁H₂₀F₃N₇O
Molecular Weight	443.43