Gemcabene calcium
Modify Date: 2024-01-02 19:06:03
Gemcabene calcium structure
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Common Name | Gemcabene calcium | ||
|---|---|---|---|---|
| CAS Number | 209789-08-2 | Molecular Weight | 340.46900 | |
| Density | N/A | Boiling Point | 453.6ºC at 760mmHg | |
| Molecular Formula | C16H28CaO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 156.7ºC | |
Use of Gemcabene calciumGemcabene calcium (PD-72953 calcium), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity[1][2][3]. |
| Name | calcium,6-(5-carboxylato-5-methylhexoxy)-2,2-dimethylhexanoate |
|---|---|
| Synonym | More Synonyms |
| Description | Gemcabene calcium (PD-72953 calcium), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity[1][2][3]. |
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| Related Catalog | |
| In Vitro | Gemcabene calcium (PD-72953 calcium) significantly downregulates hepatic mRNA markers of inflammation (TNF-α, MCP-1, MIP-1β, CCR5, CCR2, NF-κB), lipogenesis and lipid modulation (ApoC-III, ACC1, ADH-4, Sulf-2), and fibrosis (TIMP-1 and MMP-2)[3]. |
| References |
| Boiling Point | 453.6ºC at 760mmHg |
|---|---|
| Molecular Formula | C16H28CaO5 |
| Molecular Weight | 340.46900 |
| Flash Point | 156.7ºC |
| Exact Mass | 340.15600 |
| PSA | 89.49000 |
| LogP | 0.89580 |
| Vapour Pressure | 1.72E-09mmHg at 25°C |
| CI-1027 |
| UNII-Z9AM8GST2F |
| Gemcabene calcium |