Pitavastatin calcium

Modify Date: 2024-01-02 13:03:35

Pitavastatin calcium Structure
Pitavastatin calcium structure
Common Name Pitavastatin calcium
CAS Number 147526-32-7 Molecular Weight 440.49
Density N/A Boiling Point 692ºC at 760 mmHg
Molecular Formula C25H23FNO4.1/2Ca Melting Point N/A
MSDS N/A Flash Point 372.3ºC

 Use of Pitavastatin calcium


Pitavastatin Calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells.

 Names

Name pitavastatin calcium
Synonym More Synonyms

 Pitavastatin calcium Biological Activity

Description Pitavastatin Calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells.
Related Catalog
References

[1]. Mukhtar RY, et al. Pitavastatin. Int J Clin Pract. 2005 Feb;59(2):239-52.

[2]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor. Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.

 Chemical & Physical Properties

Boiling Point 692ºC at 760 mmHg
Molecular Formula C25H23FNO4.1/2Ca
Molecular Weight 440.49
Flash Point 372.3ºC
PSA 186.96000
LogP 6.36680
Storage condition -20°C

 Safety Information

Hazard Codes Xi
HS Code 2933499090

 Synthetic Route

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, calcium salt, (3R,5S,6E)- (2:1)
Pitavastatin Calcium
Livalo
Calcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate}
MFCD01937979
UNII-IYD54XEG3W
Pitavastatin (Calcium)
calcium,(E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate
Livazo
(+)-Monocalciumbis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoate}
(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid
NK-104
[3H]-Pitavastatin
Alipza
Pitavastatin hemicalcium
Nisvastatin
[14C]-Pitavastatin
(+)-Monocalcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoate}
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