254452-88-5

254452-88-5 structure

Name: Pitavastatin (3S,5R)-Isomer Calcium Salt
Chemical Name: Calcium bis{(3S,5R,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate}
CAS Number: 254452-88-5
Molecular Formula: C₂₅H₂₄FNO_4.1/₂Ca
Molecular Weight: 880.984
Catalog: Research Areas Others
Create Date: 2018-01-02 08:35:32
Modify Date: 2024-01-05 18:08:50
(3S,5S)-Pitavastatin (hemicacium) is the enantiomer of Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor[1].

Name	Calcium bis{(3S,5R,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate}
Synonyms	Calcium bis{(3S,5R,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate} 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, calcium salt, (3S,5R,6E)- (2:1) Pitavastatin Impurity 1 Pitavastatin (3S,5R)-Isomer Calcium Salt (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt

Description	(3S,5S)-Pitavastatin (hemicacium) is the enantiomer of Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Suzuki, M., et al. First systematic chiral syntheses of two pairs of enantiomers with 3,5-dihydroxyheptenoic acid chain, associated with a potent synthetic statin NK-104. Bioorganic & Medicinal Chemistry Letters. 1999;9(20), 2977–2982.