Antitumor agent-28
Modify Date: 2025-08-27 17:16:51
Antitumor agent-28 structure
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Common Name | Antitumor agent-28 | ||
|---|---|---|---|---|
| CAS Number | 2097499-67-5 | Molecular Weight | 512.62 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H32N6O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Antitumor agent-28Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity[1]. |
| Name | Antitumor agent-28 |
|---|
| Description | Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity[1]. |
|---|---|
| Related Catalog | |
| Target |
ATM ATR |
| In Vitro | Antitumor agent-28 inhibits ataxia telangiectasia mutated (ATM; IC50=7.6 nM; HT29 cells), ataxia telangiectasia and Rad3-related protein (ATR; IC50=18 μM; HT29 cells), PI3Ka (IC50=0.24 μM; BT474 cells). Antitumor agent-28 does not inhibit mTOR in MDA-MB-468 cells[1]. |
| References |
| Molecular Formula | C25H32N6O4S |
|---|---|
| Molecular Weight | 512.62 |
| InChIKey | CVJOKGCVOABDEN-UHFFFAOYSA-N |
| SMILES | CC(C)n1c(=O)n(C)c2cnc3ccc(-c4ccc(N5CC(N(C)C)C5)nc4)cc3c21.CS(=O)(=O)O |