2097499-67-5
2097499-67-5 structure
- Name: Antitumor agent-28
- Chemical Name: Antitumor agent-28
- CAS Number: 2097499-67-5
- Molecular Formula: C25H32N6O4S
- Molecular Weight: 512.62
- Catalog: Signaling Pathways Cell Cycle/DNA Damage ATM/ATR
- Create Date: 2021-09-05 18:33:55
- Modify Date: 2024-01-06 16:33:40
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Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity[1].
| Name | Antitumor agent-28 |
|---|
| Description | Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity[1]. |
|---|---|
| Related Catalog | |
| Target |
ATM ATR |
| In Vitro | Antitumor agent-28 inhibits ataxia telangiectasia mutated (ATM; IC50=7.6 nM; HT29 cells), ataxia telangiectasia and Rad3-related protein (ATR; IC50=18 μM; HT29 cells), PI3Ka (IC50=0.24 μM; BT474 cells). Antitumor agent-28 does not inhibit mTOR in MDA-MB-468 cells[1]. |
| References |
| Molecular Formula | C25H32N6O4S |
|---|---|
| Molecular Weight | 512.62 |