Astex ERK inhibitor X

Modify Date: 2024-01-06 12:44:49

Astex ERK inhibitor X structure	Common Name	Astex ERK inhibitor X
	CAS Number	2095719-90-5	Molecular Weight	550.05
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₂ClN₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Astex ERK inhibitor X

ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively[1].

Name	ERK1/2 inhibitor 1

Description	ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Stem Cell/Wnt >> ERK
Target	ERK2:3.0 nM (IC50) ERK1
In Vitro	ERK1/2 inhibitor 1 (Compound 27) shows excellent antiproliferative potency with IC50s of 4.9 and 7.5 nM in A375 and Colo205 cells, respectively[1].
References	[1]. Heightman TD, et al. Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2. J Med Chem. 2018 Jun 14;61(11):4978-4992.

Molecular Formula	C₂₉H₃₂ClN₅O₄
Molecular Weight	550.05
Storage condition	-20°C

DC Chemicals Limited
China
Product Name: Astex ERK inhibitor X
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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