201788-90-1

201788-90-1 structure

Name: Akt Inhibitor X
Chemical Name: 4-(2-chlorophenoxazin-10-yl)-N,N-diethylbutan-1-amine,hydrochloride
CAS Number: 201788-90-1
Molecular Formula: C₂₀H₂₆Cl₂N₂O
Molecular Weight: 381.33900
Catalog: Signaling Pathways JAK/STAT Signaling Pim
Create Date: 2016-09-20 06:39:54
Modify Date: 2023-01-17 21:24:48
10-DEBC is a selective Akt inhibitor. 10-DEBC shows strong inhibitory activity against Moloney murine leukemia virus (Pim) kinase-1 (IC50=1.28 μM)[1].

Name	4-(2-chlorophenoxazin-10-yl)-N,N-diethylbutan-1-amine,hydrochloride
Synonyms	Akt Inhibitor X 10-DEBC HYDROCHLORIDE

Description	10-DEBC is a selective Akt inhibitor. 10-DEBC shows strong inhibitory activity against Moloney murine leukemia virus (Pim) kinase-1 (IC50=1.28 μM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> Pim
Target	1.28 μM (Pim) [1]
References	[1]. Li, W., et al. More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors. Med. Chem. Commun. 2014;5(4):507–511.