TMPRSS6-IN-1

Modify Date: 2024-04-06 12:34:18

TMPRSS6-IN-1 Structure
TMPRSS6-IN-1 structure
Common Name TMPRSS6-IN-1
CAS Number 2088415-78-3 Molecular Weight 676.85
Density N/A Boiling Point N/A
Molecular Formula C33H40N8O4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TMPRSS6-IN-1


TMPRSS6-IN-1 (compound 8) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice[1].

 Names

Name TMPRSS6-IN-1

 TMPRSS6-IN-1 Biological Activity

Description TMPRSS6-IN-1 (compound 8) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice[1].
Related Catalog
Target

TMPRSS6 (Matriptase-2)[1]

References

[1]. St-Georges C, et al. Modulating the selectivity of matriptase-2 inhibitors with unnatural amino acids. Eur J Med Chem. 2017 Mar 31;129:110-123.  

 Chemical & Physical Properties

Molecular Formula C33H40N8O4S2
Molecular Weight 676.85
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