2088415-78-3

2088415-78-3 structure

Name: TMPRSS6-IN-1
Chemical Name: TMPRSS6-IN-1
CAS Number: 2088415-78-3
Molecular Formula: C₃₃H₄₀N₈O₄S₂
Molecular Weight: 676.85
Catalog: Signaling Pathways Metabolic Enzyme/Protease Ser/Thr Protease
Create Date: 2023-04-06 17:06:44
Modify Date: 2024-04-06 12:34:18
TMPRSS6-IN-1 (compound 8) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice[1].

Name	TMPRSS6-IN-1

Description	TMPRSS6-IN-1 (compound 8) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Others
Target	TMPRSS6 (Matriptase-2)[1]
References	[1]. St-Georges C, et al. Modulating the selectivity of matriptase-2 inhibitors with unnatural amino acids. Eur J Med Chem. 2017 Mar 31;129:110-123.

Molecular Formula	C₃₃H₄₀N₈O₄S₂
Molecular Weight	676.85