CINCHONINE MONOHYDROCHLORIDE HYDRATE

Modify Date: 2024-01-09 18:29:28

CINCHONINE MONOHYDROCHLORIDE HYDRATE Structure
CINCHONINE MONOHYDROCHLORIDE HYDRATE structure
Common Name CINCHONINE MONOHYDROCHLORIDE HYDRATE
CAS Number 206986-88-1 Molecular Weight 348.86700
Density N/A Boiling Point N/A
Molecular Formula C19H25ClN2O2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of CINCHONINE MONOHYDROCHLORIDE HYDRATE


Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis[1].

 Names

Name Hydrogen chloride (9S)-cinchonan-9-ol hydrate (1:1:1:1)

 CINCHONINE MONOHYDROCHLORIDE HYDRATE Biological Activity

Description Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis[1].
Related Catalog
References

[1]. Jin ZL, et, al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050.

 Chemical & Physical Properties

Molecular Formula C19H25ClN2O2
Molecular Weight 348.86700
Exact Mass 348.16000
PSA 45.59000
LogP 3.84020

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H332
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
RIDADR NONH for all modes of transport
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