CINCHONINE MONOHYDROCHLORIDE HYDRATE

Names

[ CAS No. ]:
206986-88-1

[ Name ]:
CINCHONINE MONOHYDROCHLORIDE HYDRATE

Biological Activity

[Description]:

Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Research Areas >> Cardiovascular Disease

Research Areas >> Infection

Research Areas >> Metabolic Disease

[References]

[1]. Jin ZL, et, al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₅ClN₂O₂

[ Molecular Weight ]:
348.86700

[ Exact Mass ]:
348.16000

[ PSA ]:
45.59000

[ LogP ]:
3.84020

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport