Propargyl-PEG6-Br

Modify Date: 2025-09-10 11:07:59

Propargyl-PEG6-Br Structure
Propargyl-PEG6-Br structure
Common Name Propargyl-PEG6-Br
CAS Number 1973383-30-0 Molecular Weight 383.28
Density N/A Boiling Point N/A
Molecular Formula C15H27BrO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG6-Br


Propargyl-PEG6-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG6-Br
Synonym More Synonyms

 Propargyl-PEG6-Br Biological Activity

Description Propargyl-PEG6-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C15H27BrO6
Molecular Weight 383.28
InChIKey VADSRAOHGSOPAQ-UHFFFAOYSA-N
SMILES C#CCOCCOCCOCCOCCOCCOCCBr

 Synonyms

MFCD32263749
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