125562-29-0
125562-29-0 structure
- Name: m-PEG6-Br
- Chemical Name: 19-Bromo-2,5,8,11,14,17-hexaoxanonadecane
- CAS Number: 125562-29-0
- Molecular Formula: C13H27BrO6
- Molecular Weight: 359.254
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-19 13:21:57
- Modify Date: 2024-01-23 10:04:52
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m-PEG6-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
| Name | 19-Bromo-2,5,8,11,14,17-hexaoxanonadecane |
|---|---|
| Synonyms |
2,5,8,11,14,17-Hexaoxanonadecane, 19-bromo-
19-Bromo-2,5,8,11,14,17-hexaoxanonadecane |
| Description | m-PEG6-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
[1]. Jennifer Riggs-Sauthier, et al. Oligomer-antihistamine conjugates. WO2008112257A1. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 385.1±37.0 °C at 760 mmHg |
| Molecular Formula | C13H27BrO6 |
| Molecular Weight | 359.254 |
| Flash Point | 158.2±25.0 °C |
| Exact Mass | 358.099091 |
| LogP | -0.89 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.459 |
| Storage condition | -20°C |