Propargyl-PEG6-N3

Modify Date: 2024-04-09 00:06:56

Propargyl-PEG6-N3 Structure
Propargyl-PEG6-N3 structure
Common Name Propargyl-PEG6-N3
CAS Number 1198080-03-3 Molecular Weight 345.391
Density N/A Boiling Point N/A
Molecular Formula C15H27N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG6-N3


Propargyl-PEG6-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-Azido-3,6,9,12,15,18-hexaoxahenicos-20-yne
Synonym More Synonyms

 Propargyl-PEG6-N3 Biological Activity

Description Propargyl-PEG6-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C15H27N3O6
Molecular Weight 345.391
Exact Mass 345.189972
LogP -1.04

 Synonyms

1-Azido-3,6,9,12,15,18-hexaoxahenicos-20-yne
3,6,9,12,15,18-Hexaoxaheneicos-20-yne, 1-azido-
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