Propargyl-PEG6-Boc

Modify Date: 2024-01-09 12:28:29

Propargyl-PEG6-Boc Structure
Propargyl-PEG6-Boc structure
Common Name Propargyl-PEG6-Boc
CAS Number 1355197-95-3 Molecular Weight 404.495
Density 1.1±0.1 g/cm3 Boiling Point 458.4±40.0 °C at 760 mmHg
Molecular Formula C20H36O8 Melting Point N/A
MSDS N/A Flash Point 194.1±27.4 °C

 Use of Propargyl-PEG6-Boc


Propargyl-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG6-t-butyl ester
Synonym More Synonyms

 Propargyl-PEG6-Boc Biological Activity

Description Propargyl-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 458.4±40.0 °C at 760 mmHg
Molecular Formula C20H36O8
Molecular Weight 404.495
Flash Point 194.1±27.4 °C
Exact Mass 404.241028
LogP 0.17
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.458

 Synonyms

4,7,10,13,16,19-Hexaoxadocos-21-yn-1-oic acid, 1,1-dimethylethyl ester
MFCD28950777
2-Methyl-2-propanyl 4,7,10,13,16,19-hexaoxadocos-21-yn-1-oate
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