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1198080-04-4

1198080-04-4 structure
1198080-04-4 structure
  • Name: Propargyl-PEG6-NH2
  • Chemical Name: 3,6,9,12,15,18-Hexaoxahenicos-20-yn-1-amine
  • CAS Number: 1198080-04-4
  • Molecular Formula: C15H29NO6
  • Molecular Weight: 319.394
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-03 22:37:48
  • Modify Date: 2023-02-06 18:26:51
  • Propargyl-PEG6-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name 3,6,9,12,15,18-Hexaoxahenicos-20-yn-1-amine
Synonyms 3,6,9,12,15,18-Hexaoxaheneicos-20-yn-1-amine
3,6,9,12,15,18-Hexaoxahenicos-20-yn-1-amine
Description Propargyl-PEG6-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.1±0.1 g/cm3
Boiling Point 401.8±40.0 °C at 760 mmHg
Molecular Formula C15H29NO6
Molecular Weight 319.394
Flash Point 190.0±21.0 °C
Exact Mass 319.199493
LogP -1.89
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.465