ZEN-3411

Modify Date: 2024-01-11 11:18:34

ZEN-3411 structure	Common Name	ZEN-3411
	CAS Number	1952264-36-6	Molecular Weight	360.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₀N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ZEN-3411

ZEN-3411 is a BET inhibitor with IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4[1].

Name	ZEN-3411

Description	ZEN-3411 is a BET inhibitor with IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	BRD4 (BD1):0.05 μM (IC50) BRD4 (BD2):0.05 μM (IC50) BRD4(BD1BD2):0.06 μM (IC50)
References	[1]. Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211.

Molecular Formula	C₂₁H₂₀N₄O₂
Molecular Weight	360.41

Hazard Codes	Xi

DC Chemicals Limited
China
Product Name: ZEN-3411
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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