ZEN-3411

Modify Date: 2025-08-25 21:18:49

ZEN-3411 Structure
ZEN-3411 structure
Common Name ZEN-3411
CAS Number 1952264-36-6 Molecular Weight 360.41
Density N/A Boiling Point N/A
Molecular Formula C21H20N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ZEN-3411


ZEN-3411 is a BET inhibitor with IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4[1].

 Names

Name ZEN-3411

 ZEN-3411 Biological Activity

Description ZEN-3411 is a BET inhibitor with IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4[1].
Related Catalog
Target

BRD4 (BD1):0.05 μM (IC50)

BRD4 (BD2):0.05 μM (IC50)

BRD4(BD1BD2):0.06 μM (IC50)

References

[1]. Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211.

 Chemical & Physical Properties

Molecular Formula C21H20N4O2
Molecular Weight 360.41

 Safety Information

Hazard Codes Xi
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