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1952264-36-6

1952264-36-6 structure
1952264-36-6 structure
  • Name: ZEN-3411
  • Chemical Name: ZEN-3411
  • CAS Number: 1952264-36-6
  • Molecular Formula: C21H20N4O2
  • Molecular Weight: 360.41
  • Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
  • Create Date: 2019-06-01 18:01:25
  • Modify Date: 2024-01-11 11:18:34
  • ZEN-3411 is a BET inhibitor with IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4[1].

Name ZEN-3411
Description ZEN-3411 is a BET inhibitor with IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4[1].
Related Catalog
Target

BRD4 (BD1):0.05 μM (IC50)

BRD4 (BD2):0.05 μM (IC50)

BRD4(BD1BD2):0.06 μM (IC50)

References

[1]. Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211.

Molecular Formula C21H20N4O2
Molecular Weight 360.41
Hazard Codes Xi