1952264-33-3

1952264-33-3 structure

1952264-33-3 structure

Name: ZEN-3862
Chemical Name: ZEN-3862
CAS Number: 1952264-33-3
Molecular Formula: C₁₉H₁₇FN₂O₃
Molecular Weight: 340.35
Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
Create Date: 2019-06-01 17:04:08
Modify Date: 2024-01-14 11:10:14
ZEN-3862 is a BET inhibitor with IC50s of 0.16 and 0.13 μM for BRD4(BD1) and BRD4(BD2) , respectively. ZEN-3862 can be used to form PROTACs to induce degradation of BRD4[1].

Name	ZEN-3862

Description	ZEN-3862 is a BET inhibitor with IC50s of 0.16 and 0.13 μM for BRD4(BD1) and BRD4(BD2) , respectively. ZEN-3862 can be used to form PROTACs to induce degradation of BRD4[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	BRD4 (BD1):0.16 μM (IC50) BRD4 (BD2):0.13 μM (IC50)
References	[1]. Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211.

Molecular Formula	C₁₉H₁₇FN₂O₃
Molecular Weight	340.35

Hazard Codes	Xi