Brexpiprazole S-oxide
Modify Date: 2025-08-26 17:55:11
Brexpiprazole S-oxide structure
|
Common Name | Brexpiprazole S-oxide | ||
|---|---|---|---|---|
| CAS Number | 1191900-51-2 | Molecular Weight | 449.565 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C25H27N3O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Brexpiprazole S-oxideBrexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human 5-HT1A and dopamine receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM[1][2][3]. |
| Name | DM-3411 |
|---|---|
| Synonym | More Synonyms |
| Description | Brexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human 5-HT1A and dopamine receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM[1][2][3]. |
|---|---|
| Related Catalog | |
| Target |
Ki: 0.12 nM (5-HT1A), 0.3 nM (D2L), 0.47 nM (5-HT2A)[2] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C25H27N3O3S |
| Molecular Weight | 449.565 |
| Exact Mass | 449.177307 |
| Index of Refraction | 1.693 |
| Benzo[b]thiophenium, 4-[4-[4-[(1,2-dihydro-2-oxo-7-quinolinyl)oxy]butyl]-1-piperazinyl]-1-hydroxy-, inner salt |
| N22UPQ09R0 |
| 4-(4-{4-[(2-Oxo-1,2-dihydro-7-quinolinyl)oxy]butyl}-1-piperazinyl)-1-benzothiophenium-1-olate |
| DM-3411 |
| UNII:N22UPQ09R0 |
| Brexpiprazole Sulfoxide |
| Brexpiprazole S-Oxide |
| Brexpiprazole Impurity 20 |