73851-70-4

73851-70-4 structure

Name: Ranitidine S-Oxide
Chemical Name: Ranitidine S-Oxide
CAS Number: 73851-70-4
Molecular Formula: C₁₃H₂₂N₄O₄S
Molecular Weight: 330.40300
Catalog: analytical chemistry Analytical reagent Ion chromatography reagent
Create Date: 2017-09-19 02:20:37
Modify Date: 2024-01-03 17:29:05
Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693). Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion[1][2].

Name	Ranitidine S-Oxide
Synonyms	(E)-1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfinyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine Ranitidine Impurity 3

Description	Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693). Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion[1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Cross DM, et al. Kinetics of ranitidine metabolism in dog and rat isolated hepatocytes. Xenobiotica. 1995 Apr;25(4):367-75. [2]. Leucuta A, et al. A pharmacokinetic interaction study between omeprazole and the H2-receptor antagonist ranitidine. Drug Metabol Drug Interact. 2004;20(4):273-81.

Density	1.265g/cm3
Boiling Point	527.5ºC at 760 mmHg
Molecular Formula	C₁₃H₂₂N₄O₄S
Molecular Weight	330.40300
Flash Point	272.8ºC
Exact Mass	330.13600
PSA	122.54000
LogP	2.64520
Index of Refraction	1.577
Storage condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Symbol	GHS07, GHS08
Signal Word	Danger
Hazard Statements	H317-H334-H335
Precautionary Statements	P261-P280-P342 + P311
Hazard Codes	Xn
Risk Phrases	37-42/43
Safety Phrases	22-36/37
RIDADR	NONH for all modes of transport