Thalidomide-O-amido-C6-NH2

Modify Date: 2025-08-26 17:58:43

Thalidomide-O-amido-C6-NH2 Structure
Thalidomide-O-amido-C6-NH2 structure
Common Name Thalidomide-O-amido-C6-NH2
CAS Number 1950635-13-8 Molecular Weight 430.45
Density N/A Boiling Point N/A
Molecular Formula C21H26N4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-O-amido-C6-NH2


Thalidomide-O-amido-C6-NH2 (Cereblon Ligand-Linker Conjugates 11), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

 Names

Name Thalidomide-O-amido-C6-NH2

 Thalidomide-O-amido-C6-NH2 Biological Activity

Description Thalidomide-O-amido-C6-NH2 (Cereblon Ligand-Linker Conjugates 11), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Cereblon

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Bradner J, et al. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses. WO 2017024318 A1.

 Chemical & Physical Properties

Molecular Formula C21H26N4O6
Molecular Weight 430.45

 Safety Information

Hazard Codes Xi
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Thalidomide-O-amido-C6-NH2 suppliers

Thalidomide-O-amido-C6-NH2 price