Amyloid β-Protein (29-40)

Modify Date: 2025-08-25 18:09:34

Amyloid β-Protein (29-40) structure	Common Name	Amyloid β-Protein (29-40)
	CAS Number	184865-04-1	Molecular Weight	1085.36000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₉H₈₈N₁₂O₁₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Amyloid β-Protein (29-40)

β-Amyloid (29-40) is a fragment of Amyloid-β peptide.

Name	amyloid β-protein(30-40)
Synonym	More Synonyms

Description	β-Amyloid (29-40) is a fragment of Amyloid-β peptide.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Amyloid-β Peptides Research Areas >> Neurological Disease
Target	Amyloid-β[1]
In Vitro	β-Amyloid (29-40) is a fragment of Amyloid-β peptide, unsoluble in water, acetonitrile or in a mixture of both in different ratios. Cationic arginine residues is introduced at β-Amyloid (29-40) C-terminus to solubilize β-Amyloid (29-40) and introduce cationicity in this Aβ stretch to enable it to interact with the negatively charged membrane of bacteria. β-Amyloid (29-40) variants shows antimicrobial effect[1]. Single chain variable fragments (scFv's) binds the 17-28 region of Abeta and effectively inhibits in vitro aggregation of Abeta, but binding the carboxyl-terminal region of β-Amyloid (29-40) does not inhibit aggregation[2].
References	[1]. Harioudh MK, et al. A short non-cytotoxic antimicrobial peptide designed from Aβ29-40 adopts a nanostructure and shows in vivo anti-endotoxin activity. Chem Commun (Camb). 2017 Dec 5;53(97):13079-13082. [2]. Liu R, et al. Single chain variable fragments against beta-amyloid (Abeta) can inhibit Abeta aggregation and prevent abeta-induced neurotoxicity. Biochemistry. 2004 Jun 8;43(22):6959-67.

Molecular Formula	C₄₉H₈₈N₁₂O₁₃S
Molecular Weight	1085.36000
Exact Mass	1084.63000
PSA	408.72000
LogP	3.13620
Storage condition	2-8℃

Aβ(30-40)

β-Amyloid (29-40)

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