SMO-IN-2

Modify Date: 2025-08-26 12:24:42

SMO-IN-2 structure	Common Name	SMO-IN-2
	CAS Number	1822355-27-0	Molecular Weight	503.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₅F₄N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SMO-IN-2

SMO-IN-2 (compound 1) is a potent smoothened (SMO) inhibitor with an IC50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1].

Name	SMO-IN-2

Description	SMO-IN-2 (compound 1) is a potent smoothened (SMO) inhibitor with an IC50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> Smo Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Hedgehog
Target	IC50: 123.4 nM (Hh)[1]
In Vitro	SMO-IN-2 (compound 1) has antiproliferative activity against human medulloblastoma cell line Daoy with an IC50 of 0.51 μM[1].
References	[1]. Ji D, et al. Design, synthesis and biological evaluation of anthranilamide derivatives as potent SMO inhibitors. Bioorg Med Chem. 2020 Mar 15;28(6):115354.

Molecular Formula	C₂₅H₂₅F₄N₅O₂
Molecular Weight	503.49

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SMO-IN-2
Price: Check
Purity: 98.64%
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.