Azido-PEG6-PFP ester

Modify Date: 2024-01-17 16:45:25

Azido-PEG6-PFP ester Structure
Azido-PEG6-PFP ester structure
Common Name Azido-PEG6-PFP ester
CAS Number 1818294-47-1 Molecular Weight 545.454
Density N/A Boiling Point N/A
Molecular Formula C21H28F5N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG6-PFP ester


Azido-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG6-PFP ester
Synonym More Synonyms

 Azido-PEG6-PFP ester Biological Activity

Description Azido-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C21H28F5N3O8
Molecular Weight 545.454
Exact Mass 545.179626
LogP 0.95

 Synonyms

3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido-, 2,3,4,5,6-pentafluorophenyl ester
Pentafluorophenyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate
MFCD26793784
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