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  • Product Name: Mal-PEG6-PFP
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1599486-33-5

1599486-33-5 structure
1599486-33-5 structure
  • Name: Mal-PEG6-PFP ester
  • Chemical Name: Mal-PEG6-PFP
  • CAS Number: 1599486-33-5
  • Molecular Formula: C25H30F5NO10
  • Molecular Weight: 599.498
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-09 00:42:57
  • Modify Date: 2024-01-03 18:12:43
  • Mal-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PEG6-PFP
Synonyms MFCD22683307
3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,3,4,5,6-pentafluorophenyl ester
Pentafluorophenyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate
Description Mal-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.4±0.1 g/cm3
Boiling Point 623.0±55.0 °C at 760 mmHg
Molecular Formula C25H30F5NO10
Molecular Weight 599.498
Flash Point 330.6±31.5 °C
Exact Mass 599.179016
LogP 0.57
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.490