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1818294-47-1

1818294-47-1 structure
1818294-47-1 structure
  • Name: Azido-PEG6-PFP ester
  • Chemical Name: Azido-PEG6-PFP ester
  • CAS Number: 1818294-47-1
  • Molecular Formula: C21H28F5N3O8
  • Molecular Weight: 545.454
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-04 23:32:14
  • Modify Date: 2025-08-25 11:10:01
  • Azido-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Azido-PEG6-PFP ester
Synonyms 3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido-, 2,3,4,5,6-pentafluorophenyl ester
Pentafluorophenyl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate
MFCD26793784
Description Azido-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C21H28F5N3O8
Molecular Weight 545.454
Exact Mass 545.179626
LogP 0.95
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