Bromo-PEG2-acid

Modify Date: 2024-01-09 18:32:52

Bromo-PEG2-acid Structure
Bromo-PEG2-acid structure
Common Name Bromo-PEG2-acid
CAS Number 1807503-92-9 Molecular Weight 241.080
Density 1.5±0.1 g/cm3 Boiling Point 347.2±27.0 °C at 760 mmHg
Molecular Formula C7H13BrO4 Melting Point N/A
MSDS N/A Flash Point 163.8±23.7 °C

 Use of Bromo-PEG2-acid


Bromo-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-[2-(2-Bromoethoxy)ethoxy]propanoic acid
Synonym More Synonyms

 Bromo-PEG2-acid Biological Activity

Description Bromo-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 347.2±27.0 °C at 760 mmHg
Molecular Formula C7H13BrO4
Molecular Weight 241.080
Flash Point 163.8±23.7 °C
Exact Mass 239.999710
LogP 0.34
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.486

 Synonyms

MFCD28122969
Propanoic acid, 3-[2-(2-bromoethoxy)ethoxy]-
3-[2-(2-Bromoethoxy)ethoxy]propanoic acid
Bromo-PEG3-acid
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