Bromo-PEG2-acetic acid

Modify Date: 2024-01-06 18:26:34

Bromo-PEG2-acetic acid Structure
Bromo-PEG2-acetic acid structure
Common Name Bromo-PEG2-acetic acid
CAS Number 2409962-85-0 Molecular Weight 227.05
Density N/A Boiling Point N/A
Molecular Formula C6H11BrO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG2-acetic acid


Bromo-PEG2-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromo-PEG2-acetic acid

 Bromo-PEG2-acetic acid Biological Activity

Description Bromo-PEG2-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Molecular Formula C6H11BrO4
Molecular Weight 227.05