5-AAM-2-CP

Modify Date: 2024-01-13 16:52:47

Use of 5-AAM-2-CP

5-AAM-2-CP is a major metabolite of Acetamiprid. Acetamiprid is a neonicotinoid insecticide used worldwide and is a nAChR agonist[1][2].

Name	N-[(6-Chloropyridin-3-yl)methyl]acetamide
Synonym	More Synonyms

Description	5-AAM-2-CP is a major metabolite of Acetamiprid. Acetamiprid is a neonicotinoid insecticide used worldwide and is a nAChR agonist[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
In Vivo	5-AAM-2-CP (5-(N-acetylaminomethyl)-2-chloropyridine) hydrolyzed product of N-desmethylacetamiprid Acetamiprid can be metabolized to 5-AAM-2-CP in both blood and urine[1].
References	[1]. Tadashi Yamamuro, et al. Simultaneous determination of neonicotinoid insecticides in human serum and urine using diatomaceous earth-assisted extraction and liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Oct 15;969:85-94. [2]. Terayama H, et al. Effect of acetamiprid on the immature murine testes. Int J Environ Health Res. 2018 Dec;28(6):683-696.

Hazard Codes	Xn
HS Code	2933399090

Acetyl chloride

CAS#:75-36-5

(2-chloropyridi...

CAS#:97004-04-1

5-AAM-2-CP

CAS#:175424-74-5

Literature: US5623076 A1, ;

(6-Chloro-3-pyr...

CAS#:33252-28-7

Ethanoic anhydride

CAS#:108-24-7

~27%

5-AAM-2-CP

CAS#:175424-74-5

Precursor 4
CAS#:75-36-5 Acetyl chloride CAS#:97004-04-1 (2-chloropyridi... CAS#:33252-28-7 (6-Chloro-3-pyr... CAS#:108-24-7 Ethanoic anhydride
DownStream 1
CAS#:70258-18-3 2-Chloro-5-chlo...

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-chloro-5-acetaminomethylpyridine

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Price: ￥800/50 mg

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