CCT 018159

Modify Date: 2024-01-05 16:13:37

CCT 018159 structure	Common Name	CCT 018159
	CAS Number	171009-07-7	Molecular Weight	352.384
	Density	1.3±0.1 g/cm3	Boiling Point	547.3±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₀N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	284.8±30.1 °C

Use of CCT 018159

CCT018159, a 3,4-diaryl pyrazoleresorcinol, is a ATP-competitive HSP90 ATPase activity inhibitor with IC50s of 3.2 and 6.6 µM for human Hsp90β and yeast Hsp90, respectively. CCT018159 caused cell cytostasis associated with a G1 arrest and induces apoptosis. CCT018159 inhibits key endothelial and tumor cell functions implicated in invasion and angiogenesis[1].

Name	cct-018159
Synonym	More Synonyms

Description	CCT018159, a 3,4-diaryl pyrazoleresorcinol, is a ATP-competitive HSP90 ATPase activity inhibitor with IC50s of 3.2 and 6.6 µM for human Hsp90β and yeast Hsp90, respectively. CCT018159 caused cell cytostasis associated with a G1 arrest and induces apoptosis. CCT018159 inhibits key endothelial and tumor cell functions implicated in invasion and angiogenesis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	human Hsp90β:3.2 μM (IC50) yeast Hsp90:6.6 μM (IC50)
References	[1]. Swee Y Sharp, et al. In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors. Cancer Res. 2007 Mar 1;67(5):2206-16.

Density	1.3±0.1 g/cm3
Boiling Point	547.3±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₀N₂O₄
Molecular Weight	352.384
Flash Point	284.8±30.1 °C
Exact Mass	352.142303
PSA	87.60000
LogP	2.79
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.647

4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL

4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-1,3-benzenediol

4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethylbenzene-1,3-diol

CCT-018159

CCT 018159,4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-1,3-benzenediol

1,3-Benzenediol, 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-

DC Chemicals Limited
China
Product Name: CCT-018159
Price: $Inquiry/100mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: CCT 018159
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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