Hydroxy-PEG3-acrylate structure
|
Common Name | Hydroxy-PEG3-acrylate | ||
|---|---|---|---|---|
| CAS Number | 16695-45-7 | Molecular Weight | 204.22000 | |
| Density | 1.098g/cm3 | Boiling Point | 302.4ºC at 760mmHg | |
| Molecular Formula | C9H16O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 113ºC | |
Use of Hydroxy-PEG3-acrylateHydroxy-PEG3-acrylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-(2-hydroxyethoxy)ethoxy]ethyl prop-2-enoate |
|---|---|
| Synonym | More Synonyms |
| Description | Hydroxy-PEG3-acrylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.098g/cm3 |
|---|---|
| Boiling Point | 302.4ºC at 760mmHg |
| Molecular Formula | C9H16O5 |
| Molecular Weight | 204.22000 |
| Flash Point | 113ºC |
| Exact Mass | 204.10000 |
| PSA | 64.99000 |
| Vapour Pressure | 9.63E-05mmHg at 25°C |
| Index of Refraction | 1.453 |
| InChIKey | VETIYACESIPJSO-UHFFFAOYSA-N |
| SMILES | C=CC(=O)OCCOCCOCCO |
| HS Code | 2916129000 |
|---|
|
~48%
Hydroxy-PEG3-ac... CAS#:16695-45-7 |
| Literature: Philippon, Annie; Tao, Jingchao; Tetard, David; Degueil-Castaing, Marie; Maillard, Bernard Synthetic Communications, 1997 , vol. 27, # 15 p. 2651 - 2682 |
|
~%
Hydroxy-PEG3-ac... CAS#:16695-45-7
Detail
|
| Literature: BASF AKTIENGESELLSCHAFT Patent: WO2004/14837 A1, 2004 ; Location in patent: Page/Page column 19-20 ; |
| HS Code | 2916129000 |
|---|---|
| Summary | 2916129000 other esters of acrylic acid VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
| ethylenediglycol acrylate |
| EINECS 240-741-9 |
| 2-(2-(2-Hydroxyethoxy)ethoxy)ethyl acrylate |
| triethylene glycol monoacrylate |