16695-45-7
16695-45-7 structure
- Name: Hydroxy-PEG3-acrylate
- Chemical Name: 2-[2-(2-hydroxyethoxy)ethoxy]ethyl prop-2-enoate
- CAS Number: 16695-45-7
- Molecular Formula: C9H16O5
- Molecular Weight: 204.22000
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-11-29 00:39:56
- Modify Date: 2024-04-02 17:18:46
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Hydroxy-PEG3-acrylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-(2-hydroxyethoxy)ethoxy]ethyl prop-2-enoate |
|---|---|
| Synonyms |
ethylenediglycol acrylate
EINECS 240-741-9 2-(2-(2-Hydroxyethoxy)ethoxy)ethyl acrylate triethylene glycol monoacrylate |
| Description | Hydroxy-PEG3-acrylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.098g/cm3 |
|---|---|
| Boiling Point | 302.4ºC at 760mmHg |
| Molecular Formula | C9H16O5 |
| Molecular Weight | 204.22000 |
| Flash Point | 113ºC |
| Exact Mass | 204.10000 |
| PSA | 64.99000 |
| Vapour Pressure | 9.63E-05mmHg at 25°C |
| Index of Refraction | 1.453 |
| HS Code | 2916129000 |
|---|
|
~48%
16695-45-7 |
| Literature: Philippon, Annie; Tao, Jingchao; Tetard, David; Degueil-Castaing, Marie; Maillard, Bernard Synthetic Communications, 1997 , vol. 27, # 15 p. 2651 - 2682 |
|
~%
16695-45-7
Detail
|
| Literature: BASF AKTIENGESELLSCHAFT Patent: WO2004/14837 A1, 2004 ; Location in patent: Page/Page column 19-20 ; |
| HS Code | 2916129000 |
|---|---|
| Summary | 2916129000 other esters of acrylic acid VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |