Epi-galantamine

Modify Date: 2024-01-13 17:17:13

Epi-galantamine structure	Common Name	Epi-galantamine
	CAS Number	1668-85-5	Molecular Weight	287.35400
	Density	1.28g/cm3	Boiling Point	439.3ºC at 760 mmHg
	Molecular Formula	C₁₇H₂₁NO₃	Melting Point	183-185ºC
	MSDS	N/A	Flash Point	219.5ºC

Use of Epi-galantamine

Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45.7 μM[1][2][3].

Name	Epi Galanthamine
Synonym	More Synonyms

Description	Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC50 of 45.7 μM[1][2][3].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	EC50: 45.7 μM (AChE)[1]
References	[1]. Thomsen T, et al. Stereoselectivity of cholinesterase inhibition by galanthamine and tolerance in humans. Eur J Clin Pharmacol. 1990;39(6):603-5. [2]. Berkov S, et al. Rapid TLC/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts. Phytochem Anal. 2008 Sep-Oct;19(5):411-9. [3]. Maláková J, et al. High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 15;853(1-2):265-74.

Density	1.28g/cm3
Boiling Point	439.3ºC at 760 mmHg
Melting Point	183-185ºC
Molecular Formula	C₁₇H₂₁NO₃
Molecular Weight	287.35400
Flash Point	219.5ºC
Exact Mass	287.15200
PSA	41.93000
LogP	1.78820
Vapour Pressure	1.71E-08mmHg at 25°C
Index of Refraction	1.636
Storage condition	-20°C