STAT6-IN-1

Modify Date: 2024-04-05 18:07:39

STAT6-IN-1 structure	Common Name	STAT6-IN-1
	CAS Number	1637532-68-3	Molecular Weight	745.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₃H₃₇IN₃O₇P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of STAT6-IN-1

STAT6-IN-1 (compound 19a) is a STAT6 inhibitor with a high affinity for the SH2 domain of STAT6 (IC50=0.028 µM). STAT6-IN-1 can be used in studies of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease or cancer[1][2].

Name	STAT6-IN-1

Description	STAT6-IN-1 (compound 19a) is a STAT6 inhibitor with a high affinity for the SH2 domain of STAT6 (IC50=0.028 µM). STAT6-IN-1 can be used in studies of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease or cancer[1][2].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> STAT Research Areas >> Inflammation/Immunology
Target	IC50: 0.028 µM (SH2)[1].
References	[1]. Mandal PK, et al. Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity. J Med Chem. 2015 Nov 25;58(22):8970-84. [2]. John S, et al. Stat6 inhibitors. Patent WO2014182928A2.

Molecular Formula	C₃₃H₃₇IN₃O₇P
Molecular Weight	745.54

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STAT6-IN-1

Use of STAT6-IN-1

Names

STAT6-IN-1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.