Propargyl-PEG2-urea-C3-triethoxysilane

Modify Date: 2024-01-10 13:34:11

Propargyl-PEG2-urea-C3-triethoxysilane Structure
Propargyl-PEG2-urea-C3-triethoxysilane structure
Common Name Propargyl-PEG2-urea-C3-triethoxysilane
CAS Number 1637329-79-3 Molecular Weight 390.55
Density N/A Boiling Point N/A
Molecular Formula C17H34N2O6Si Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG2-urea-C3-triethoxysilane


Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG2-urea-C3-triethoxysilane

 Propargyl-PEG2-urea-C3-triethoxysilane Biological Activity

Description Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H34N2O6Si
Molecular Weight 390.55