Propargyl-PEG2-beta-D-glucose

Modify Date: 2024-01-09 10:42:16

Propargyl-PEG2-beta-D-glucose Structure
Propargyl-PEG2-beta-D-glucose structure
Common Name Propargyl-PEG2-beta-D-glucose
CAS Number 2353409-73-9 Molecular Weight 306.31
Density N/A Boiling Point N/A
Molecular Formula C13H22O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG2-beta-D-glucose


Propargyl-PEG2-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG2-beta-D-glucose

 Propargyl-PEG2-beta-D-glucose Biological Activity

Description Propargyl-PEG2-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H22O8
Molecular Weight 306.31