PF-06446846 hydrochloride

Modify Date: 2023-02-25 23:04:58

PF-06446846 hydrochloride Structure
PF-06446846 hydrochloride structure
Common Name PF-06446846 hydrochloride
CAS Number 1632250-50-0 Molecular Weight 433.893
Density 1.5±0.1 g/cm3 Boiling Point 655.5±65.0 °C at 760 mmHg
Molecular Formula C22H20ClN7O Melting Point N/A
MSDS N/A Flash Point 350.2±34.3 °C

 Use of PF-06446846 hydrochloride


PF-06446846 (PF-6446846) is a potent, highly selective inhibitor of PCSK9 translation with IC50 of 0.3 uM for inhibition the secretion of PCSK9 by Huh7 cells.

 Names

Name PF-06446846 hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 655.5±65.0 °C at 760 mmHg
Molecular Formula C22H20ClN7O
Molecular Weight 433.893
Flash Point 350.2±34.3 °C
Exact Mass 433.141785
LogP 1.86
Appearance of Characters powder,white to beige
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.745
Storage condition room temp

 Synonyms

Benzamide, N-(3-chloro-2-pyridinyl)-N-[(3R)-3-piperidinyl]-4-(3H-1,2,3-triazolo[4,5-b]pyridin-3-yl)-
N-(3-Chloro-2-pyridinyl)-N-[(3R)-3-piperidinyl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide