PF-CBP1 hydrochloride
Modify Date: 2025-08-25 09:54:14
PF-CBP1 hydrochloride structure
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Common Name | PF-CBP1 hydrochloride | ||
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| CAS Number | 2070014-93-4 | Molecular Weight | 525.08 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H36N4O3·HCl | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-CBP1 hydrochloridePF-CBP1 hydrochloride is a highly selective inhibitor of the CREB binding protein bromodomain.Target: CREBin vitro: PF-CBP1 modulates key inflammatory genes in primary macrophages. PF-CBP1 downregulates RGS4 in neurons, a target linked to Parkinson's disease. PF-CBP1 is 139-fold selective over BRD4 in the biochemical assays and >105-fold selective by ITC. F-CBP1 is also a potent inhibitor of EP300 (a result observed for other CBP inhibitors. [1] |
| Name | PF-CBP1 hydrochloride |
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| Synonym | More Synonyms |
| Description | PF-CBP1 hydrochloride is a highly selective inhibitor of the CREB binding protein bromodomain.Target: CREBin vitro: PF-CBP1 modulates key inflammatory genes in primary macrophages. PF-CBP1 downregulates RGS4 in neurons, a target linked to Parkinson's disease. PF-CBP1 is 139-fold selective over BRD4 in the biochemical assays and >105-fold selective by ITC. F-CBP1 is also a potent inhibitor of EP300 (a result observed for other CBP inhibitors. [1] |
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| Related Catalog | |
| References |
| Molecular Formula | C29H36N4O3·HCl |
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| Molecular Weight | 525.08 |
| InChIKey | HFOZCHHWLMTUTP-UHFFFAOYSA-N |
| SMILES | CCCOc1ccc(CCc2nc3cc(-c4c(C)noc4C)ccc3n2CCN2CCOCC2)cc1.Cl |
| Storage condition | -20℃ |
| 4-(2-(5-(3,5-Dimethylisoxazol-4-yl)-2-(4-propoxyphenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine hydrochloride |