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862282-10-8

862282-10-8 structure
862282-10-8 structure
  • Name: PF-00446687 hydrochloride
  • Chemical Name: [(4R)-4-(2,4-Difluorophenyl)-1-(2-methyl-2-propanyl)-3-pyrrolidin yl][(3R,5S)-4-hydroxy-3,5-dimethyl-4-phenyl-1-piperidinyl]methano ne hydrochloride (1:1)
  • CAS Number: 862282-10-8
  • Molecular Formula: C28H37ClF2N2O2
  • Molecular Weight: 507.05500
  • Create Date: 2017-11-25 13:52:22
  • Modify Date: 2025-09-07 22:17:33
  • PF-00446687 hydrochloride (PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM.

Name [(4R)-4-(2,4-Difluorophenyl)-1-(2-methyl-2-propanyl)-3-pyrrolidin yl][(3R,5S)-4-hydroxy-3,5-dimethyl-4-phenyl-1-piperidinyl]methano ne hydrochloride (1:1)
Molecular Formula C28H37ClF2N2O2
Molecular Weight 507.05500
Exact Mass 506.25100
PSA 43.78000
LogP 5.45870
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