GSK-2793660

Modify Date: 2024-04-02 19:15:04

GSK-2793660 structure	Common Name	GSK-2793660
	CAS Number	1613458-70-0	Molecular Weight	357.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₇N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GSK-2793660

GSK-2793660 is an oral, irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 can be used for the research of bronchiectasis[1][2].

Name	GSK-2793660

Description	GSK-2793660 is an oral, irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 can be used for the research of bronchiectasis[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
Target	Cathepsin C (CTSC)[1][2]
In Vivo	GSK-2793660 is a cathepsin C (also known as dipeptidyl peptidase I enzyme) inhibitor for the reaearch of cystic fibrosis, non-cystic fibrosis bronchiectasis, anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis and bronchiectasis[1].
References	[1]. Szcześniak P, et al. The Synthesis of α,α-Disubstituted α-Amino Acids via Ichikawa Rearrangement. J Org Chem. 2016 Feb 5;81(3):1057-74. [2]. Miller BE, et al. Epithelial desquamation observed in a phase I study of an oral cathepsin C inhibitor (GSK2793660). Br J Clin Pharmacol. 2017 Dec;83(12):2813-2820.

Molecular Formula	C₂₀H₂₇N₃O₃
Molecular Weight	357.45

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GSK-2793660
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Purity: 98.0%
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