1613458-79-9

1613458-79-9 structure

Name: GSK 2793660
Chemical Name: 4-Amino-N-[(2E,4S)-1-(2,3-dihydro-1H-indol-1-yl)-6-methyl-1-oxo-2-hepten-4-yl]tetrahydro-2H-pyran-4-carboxamide hydrochloride (1:1)
CAS Number: 1613458-79-9
Molecular Formula: C₂₂H₃₂ClN₃O₃
Molecular Weight: 421.96
Create Date: 2018-07-05 02:06:15
Modify Date: 2024-02-01 18:04:22
GSK2793660 hydrochloride is an orally active, irreversible cathepsin C (CTSC) inhibitor for bronchodilation studies[1].

Name	4-Amino-N-[(2E,4S)-1-(2,3-dihydro-1H-indol-1-yl)-6-methyl-1-oxo-2-hepten-4-yl]tetrahydro-2H-pyran-4-carboxamide hydrochloride (1:1)
Synonyms	4-Amino-N-[(2E,4S)-1-(2,3-dihydro-1H-indol-1-yl)-6-methyl-1-oxo-2-hepten-4-yl]tetrahydro-2H-pyran-4-carboxamide hydrochloride (1:1) 2H-Pyran-4-carboxamide, 4-amino-N-[(1S,2E)-4-(2,3-dihydro-1H-indol-1-yl)-1-(2-methylpropyl)-4-oxo-2-buten-1-yl]tetrahydro-, hydrochloride (1:1) GSK 2793660

Description	GSK2793660 hydrochloride is an orally active, irreversible cathepsin C (CTSC) inhibitor for bronchodilation studies[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
References	[1]. Bruce E Miller, et al. Epithelial desquamation observed in a phase I study of an oral cathepsin C inhibitor (GSK2793660). Br J Clin Pharmacol. 2017 Dec;83(12):2813-2820.