Cecropin A (1-7)-Melittin A (2-9) amide trifluoroacetate salt

Modify Date: 2025-08-23 18:08:45

Cecropin A (1-7)-Melittin A (2-9) amide trifluoroacetate salt structure	Common Name	Cecropin A (1-7)-Melittin A (2-9) amide trifluoroacetate salt
	CAS Number	157606-25-2	Molecular Weight	1770.30000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈₉H₁₅₂N₂₂O₁₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cecropin A (1-7)-Melittin A (2-9) amide trifluoroacetate salt

Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides[1].

Name	cecropin a (1-7)-melittin a (2-9) amide
Synonym	More Synonyms

Description	Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Cecropin A (1-7)-Melittin A (2-9) (0-64 mg/L, 48 h) 作用于E. coli ATCC 25922, Staphylococcus aureus ATCC 29213, B. fragilis NCTC 9343 和 C. pefringens ATCC 13124 的 MIC 值分别为 8 mg/L, 32 mg/L, 8 mg/L and 64 mg/L[1]。
References	[1]. Charlotta Edlund, et al. Antianaerobic activity of a cecropin---melittin peptide. Clin Microbiol Infect. 1998 Apr;4(4):181-185.

Molecular Formula	C₈₉H₁₅₂N₂₂O₁₅
Molecular Weight	1770.30000
Exact Mass	1769.18000
PSA	622.40000
LogP	10.72030
InChIKey	WMTUWZOBAVPERW-VZYQMWHSSA-N
SMILES	CCC(C)C(NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(N)CCCCN)C(=O)NCC(=O)NC(C)C(=O)NC(C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(CC(C)C)C(N)=O)C(C)C)C(C)C

Fmoc-Gly-OH

CAS#:29022-11-5

Fmoc-Val-OH

CAS#:68858-20-8

Fmoc-Leu-OH

CAS#:35661-60-0

Fmoc-Ala-OH

CAS#:35661-39-3

FMOC-L-Phenylalanine

CAS#:35661-40-6

Detail

Literature: Fernandez-Reyes, Maria; Diaz, Dolores; De La Torre, Beatriz G.; Cabrales-Rico, Ania; Valles-Miret, Mariona; Jimenez-Barbero, Jesus; Andreu, David; Rivas, Luis Journal of Medicinal Chemistry, 2010 , vol. 53, # 15 p. 5587 - 5596

Precursor 8
CAS#:29022-11-5 Fmoc-Gly-OH CAS#:68858-20-8 Fmoc-Val-OH CAS#:35661-60-0 Fmoc-Leu-OH CAS#:35661-39-3 Fmoc-Ala-OH
CAS#:35661-40-6 FMOC-L-Phenylalanine CAS#:71989-23-6 Fmoc-Ile-OH CAS#:71989-26-9 Fmoc-Lys(Boc)-OH CAS#:143824-78-6 Fmoc-Trp(Boc)-OH
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